Indoor cannabis cultivation has recently seen a boom in popularity. Some attribute it to legalization, others to the increase in demand. Regardless of the reason, it’s led to some amazing new variants.


It’s hard to pinpoint what makes a specific weed type “the best.” There is an incredible range of strains, all with different benefits. Therefore, we’ll focus on the best indoor strains for yield and potency.


Why grow marijuana indoors?

There are different reasons to grow cannabis indoors, from overcoming climate difficulties to compensating for seasonal shortages in light. People living in cities also often lack outside space to start a sizable crop. For those in the urban jungle, the best indoor strains are perfect for cultivating inside your house.


Unlike growing marijuana outdoors, an indoor setup gives you full control. With that in mind, good lights, an efficient ventilation system, and high-quality seeds are essential for a fruitful harvest. Fortunately, retailers like SeedSupreme have the best indoor cannabis strains and offer helpful tips for newbies.


The best cannabis strains for growing indoors

While it’s possible to grow pretty much any weed strain indoors, not all are ideal in such setups. Many variants thrive outside and should stay there, but some are better inside because of their fragility. In most cases, though, the best indoor strains of 2021 are robust and flourish inside or outside.


Although there’s no single “best indoor yield” strain, there are many competitors for the title. You can buy the best indoor strain for yield and potency, but use a garbage setup and have terrible outcomes. Similarly, you can use local landrace seeds, but with a mindful setup, you’ll harvest decent colas. The truth is, results heavily depend on how you cultivate your cannabis plants.


We always recommend beginners thoroughly research indoor cultivation methods. Depending on your nutrients, light, grow medium, etc., the THC and CBD levels may vary. To give you the most accurate information available, we’ll use statistical averages.


Additionally, to avoid the heartache of accidental males, we’ll stick with feminized and autoflowering strains. Finally, we’ll consider the possibility that the scent of bud might fill your home when harvest time draws near. Now that we’ve established the basic requirements (i.e., have a decent setup), let’s look at the best indoor strains of 2021:


5. Shishkaberry Kush Feminized

When most people hear the word “berry,” the imagination is so specific that nothing compares. And for Shishkaberry Kush, that’s how it is. An absolute delight inside the house, this baby deserves to be on the list of best indoor weed strains.


Type Indica Dominant
Genes Blueberry x Afghani Kush
Yield 14 - 22 oz / 10 sq ft
THC 26%
CBD 0.1%
Flowering time 56 - 70 days
Mediums Hydroponics / Coco coir / Soil
Scent Berries, Herbal, Earthy
Difficulty Easy to medium


Initially, it creates an uplifting, pleasant high that sharpens your focus, but the heavy couch lock quickly replaces that. Considered one of the most flavorful weed strains, the smell of the buds is very pleasant. Cultivators enjoy growing Shishkaberry Kush because of its quick flowering time and generous yields. 


4. Sweet Tooth Autoflower

As a definite must-grow, Sweet Tooth Autoflower is up there with the best indoor cannabis strains. Regardless of the season, because it’s an autoflowering strain, your ganja is guaranteed to go into the flowering stage to make buds. Your main duty is to ensure it gets what’s needed to make them massive. Fruity, floral, and full of fragrance, Sweet Tooth is a joy to cultivate indoors.


Type Mostly Indica
Genes Afghan Kush x Hawaiian Sativa x Nepali Indica x Unknown Ruderalis
Yield 12 - 23 oz / 10 sq ft
THC 20%
CBD 0.5%
Flowering time 72 - 86 days
Mediums Hydroponics / Soil
Scent Tropical, Sweet, Floral
Difficulty Easy to medium


As a ruderalis derivative, it’s adapted to the harsh climates of the Arctics, utilizing maximum sunlight during summer. To make the most of the autoflower abilities of Sweet Tooth, expose it to at least 17 hours of light daily.  High harvests and intense THC levels make it worth considering as one of the best indoor strains for yield and potency.



3. Grizzly Purple Autoflower

You may wonder why Grizzly Purple Autoflower is on the list for best marijuana strains of 2021. Simply put, it’s beautiful and smells amazing. The colas develop into colorful shades of violet and fill the air with the sweet scent of lemon.


Type Mostly Indica
Genes Critical Autoflower  x Purple Afghan Kush x Unknown Ruderalis
Yield 11 - 21 oz / 10 sq ft
THC 20%
CBD 0.3%
Flowering time 70 - 80 days
Mediums Soil / Hydroponics / Coco coir
Scent Lemon, Fruity, Citrusy
Difficulty Easy to medium


Being adapted to extremely cold environments, this is one of the hardiest autoflower variants around. Perfect for the SOG (Sea Of Green) method, they’re resistant to mold and produce thick resin layers. The fact that it changes color in cold temperatures puts it high on the list as one of the best indoor cannabis strains.



2. Strawberry Cough Feminized

A fairly new breed, Strawberry Cough packs an incredible punch, particularly to the chest, and is a worldwide classic. While the scent can be fairly thick during bloom, it’s not unpleasant. Simple to grow and maintain, it’s easily one of the best indoor cannabis strains.


Type Mostly Sativa
Genes Erdbeer x Unknown Indica
Yield 14 - 18 oz / 10 sq ft
THC 25%
CBD 0.5%
Flowering time 63 days
Mediums Coco coir / Soil / Hydroponics
Scent Strawberry, Spicy, Sweet
Difficulty Medium to experienced


If you have the vertical space, this sativa dominant hybrid can grow quite tall. Alternatively, topping can keep it short and foliage bushy. Popular among cannabis enthusiasts, Strawberry Cough is up there with the best indoor cannabis strains.



1. Northern Lights x Blueberry Autoflower

A combination of two of the most epic ganja varieties out there, Northern Lights x Blueberry Auto stems from the same strains in the name. Not only is it an extremely fast grower, but it always flowers, and the colas can become massive. That, among various other factors, makes Northern Lights x Blueberry Autoflower one of the best indoor strains for beginners.


Type Mostly Indica
Genes Blueberry Auto x  Northern Lights Auto
Yield 14 - 17 oz / 10 sq ft
THC 18%
CBD 0.3%
Flowering time 70 - 84 days
Mediums Coco coir / Soil / Hydroponics
Scent Fruity, Spicy, Berries
Difficulty Easy to Expert


Its short lifespan means even the most novice gardeners, with a constrained budget, can yield a fair amount. Experts with advanced gear and loads of space can harvest more. Either way, it’s easily the best all-around indoor strain to cultivate.



Where to find the best marijuana strains

To access the wonderful world of growing the best indoor marijuana strains, you only need to familiarize yourself with the internet and make sure it’s legal in your area. Thanks to modern advancements, online retailers such as SeedSupreme can offer discreet shipping anywhere in the USA.


Whether you want to learn how to grow cannabis or want to visit an extremely varied seed bank, technology lets you do it with just a click.


Time to get indoors

Growing the best indoor strain of marijuana has never been easier, nor has it been more difficult. It’s easy because you can buy everything needed at a local nursery or even online. It’s difficult because it’s hard to choose the “best indoor cannabis strain” when there are so many amazing ones.

Learn now how to get started with our beginner's guide to growing weed indoors.

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