The question of the best hybrid strains depends on who you ask. Some believe that potent strains are better, while others make this judgment based on the effects. 

The fact is that these exotic buds often deliver multi-dimensional effects, so the results are extraordinary. These hybrid cannabis seeds may be a mix of strains, but their holistic properties are highly sought after.

So how do you know if you have one of the top hybrid strains? Join us as we explore the top ten best hybrid weed strains. Whether you’re after specific effects or some potent buds, you’ll find something on this list.

Let's get started.

White Widow

White Widow cannabis hybrid strain

Not only is White Widow one of the best hybrid strains, but also one of the most potent.  If you're a cannabis enthusiast, you're probably familiar with this strain, and if not, you're in for a divine surprise.

White Widow is a connoisseur’s delight, thanks to its potent yet balanced effects. The cultivar’s alluring sweet and spicy aroma is enough to leave you wanting more. 

With THC levels around 25%, White Widow offers a surge of energy before strapping you into a comfortable and euphoric couch lock. The aroma is very herbal and earthy, with subtle fruit notes provided by the terpenes of White Widow.

White widow seeds are straightforward for expert and rookie gardeners looking to harvest successful and powerful yields of marijuana buds. 

Consumers report they feel an increase in physical and mental stimulation, which may help combat feelings of depression and stress.


Gorilla Glue

gorilla glue cannabis hybrid strain

Gorilla Glue #4 is a multi-award-winning cultivar that promises enchanting sensations with a high-THC level of between 25–and 30%. This cultivar is one of the best hybrid weed strains to consume if you seek an uplifting and energizing effect.

Cross breeders combined Sour Dubble, Chem’s Sister, and Chocolate Diesel to create a positive, uplifting, and relaxed cannabis strain. This cultivar is one of the best 50/50 hybrid strains, which contains a perfect balance of indica and sativa genetics.

Users report this marijuana is an attractive option for nighttime, as it takes you on a relaxing cerebral ride into dreamland. A couple of puffs is enough to induce euphoric energy waves that melt away tension and negativity.

True to its indica genetics, Gorilla Glue #4 develops thick, dense buds coated with a crystalline layer of trichomes. Upon lighting up, you’ll soon find yourself engulfed with a coffee-like aroma and flavor. 

Take it slow with this powerful cultivar, as its intense mind and body buzz shines for a couple of hours after smoking. Indulging in Gorilla Glue may have slight adverse effects, so it's important to keep hydrated and use eye drops.


Wedding Cake

wedding cake cannabis hybrid strain

Wedding Cake is one of the best hybrid strains to consume, containing 60% indica and 40% sativa genetics with 22% THC. This potent marijuana crosses two delightful strains, Wedding Cake and Grape Pie, which pass down their divine fruity flavors.

If you have a sweet tooth, smoking Wedding Pie strain satisfies your palate and leaves you in clouds of bliss. This weed is a fast-acting bud that releases rich berry and grape aromas that combine to give you a breathtaking experience.

Users report that Wedding Pie cannabis is perfect for inducing relaxation and melts away tension and negative thoughts.

This cannabis cultivar is a top choice for medicinal smokers who struggle with eating disorders. Its high-THC buds increase your appetite and desire for a variety of foods.

Wedding Pie might be the perfect solution for insomniacs, as a couple of puffs are enough to rest your mind and body.


Jack Herer (aka The Jack)

Jack Herer cannabis hybrid strain

Jack Herer feminized provides various stunning effects for both recreational and medical users. This cultivar is one of the best sativa-dominant hybrid strains that promises exceptional sensations and may relieve depression and anxiety. 

The Jack is a sativa-leaning hybrid born from blending the famous Northern lights #5, Haze, and Shiva Skunk, containing around 23% THC. This popular weed strain has won several Cannabis Cup awards and was created to honor the cannabis activist Jack Herer.

Expect to feel an overwhelming euphoria wash over you as your body starts to release aches and pains. Jack Herer is suitable as a daytime toke or after work, delivering a rush of creativity and extreme pleasure.

These resinous nugs offer an energizing effect on the mind and body, ideal for those who wish to stay productive and motivated. After smoking these potent buds, expect to get through your day with ease and liveliness.

Medicinal users swear by the strain’s many holistic benefits. It might positively shift mood disorders and doubtful thoughts and aid those with chronic stress.

Enjoying this sativa-charged strain may also assist with eating disorders and nausea by increasing appetite and making meals tastier.


Blue dream

Blue Dream cannabis hybrid strain

Considered one of the best sativa-dominant hybrid strains, the Blue Dream is popular for its unique aromatic and flavor profile. It produces a unique combination of sandalwood, citrus, and floral notes. 

As a combination of the iconic Blueberry and Haze strains, Blueberry Dream contains 60% sativa and 40% indica genetics. This cannabis cultivar is a potent medical strain with various potential benefits, such as anxiety relief, the onset of happiness, and well-being.

Blue Dream is an outstanding weed plant, considered among the best sativa hybrid strains, with a THC level of around 23%. This cultivar’s energizing effects allow you to align, stay motivated, and focus on the day.

This strain is an ideal solution for busy days and when you’re looking to relieve stress or anxiety. Blue Dream cannabis leaves you feeling creative, relaxed, and inspired. It’s the best solution on days when you need an extra kick.

Consumer reports that this marijuana strain may help those who struggle with mood disorders, depression, and stressful conditions.


Fire OG

Fire OG cannabis hybrid strain

Fire OG feminized is among the best hybrid strains of 2022 with its legendary indica parents—San Fernando Valley OG Kush and OG Kush. With an average THC around 23%, this cultivar is one of the most potent members of the OG family. 

If you’re looking for a long-lasting chill-out strain, this is the bud for you. Just remember that moderation is key. While a toke may ignite a cerebral boost, it also delivers sedative effects—making it best suited for evening or weekend use. 

When the buds are close to harvest, they’re covered in frosty red hairs, giving the strain its name. It may not be the easiest to cultivate, but it’s worth all the hassle. With a bit of know-how and extra effort, you’ll soon be ready for a fruitful harvest.

True to the OG family, this cultivar leaves you with hash-like, spicy notes. With each toke, you’ll also enjoy a cloud of smoke with hints of citrus, musk, and earth. This may be a pungent combination, but it’s also invigorating and welcoming.


OG Kush

OG Kush cannabis hybrid strain

You can’t discuss the best indica hybrid strains without looking at OG Kush. With 22% THC, it delivers a fabulous frontal lobe buzz, transforming into a relaxing ride.

This cultivar is indica-dominant with 75% indica and 25% sativa genetics. Breeders crossed Chemdawg, Hindu Kush, and Lemon Thai to create this powerful sedative cultivar.

Lighting this bud releases rich lemon and spicy notes, leaving a citrus tang lingering on your tongue. The effects of OG Kush start with a numbing body buzz that’ll have you walking on clouds and extremely relaxed. 

This cannabis is best for nighttime use, which allows you to benefit from its calming and stress-busting sensations. After smoking this kush, stay indoors and cool off, as the long-lasting sedative effects daze you into dreamland.

Medical users report that this indica cannabis may assist with increasing appetite, reducing anxious thoughts, and may induce rejuvenating sleep.


Cherry Pie

cherry pie cannabis hybrid strain

Cherry Pie is one of the best hybrid strains, resulting from breeders blending Grand Daddy Purple and Durban Poison. This cannabis strain is a heavy indica-dominant cultivar with 80% indica and 20% sativa genetics.

Cherry Pie is known for its flavor-packed buds containing between 20–26% THC level, offering the best characteristics from its lineage. After smoking these delicious nugs, you immediately feel a shift of perception as a cheery smile graces your face.

This indica cultivar produces small to medium densely packed nugs wrapped in bright orange pistils. These colorful buds are coated in glistening trichomes during the flowering phase, exuding sweet herbal and floral aromas.

Once lit up, Cherry pie cannabis lets off a smooth fruity taste and, on the exhale, an intense tropical flavor. After a few minutes of consuming, tokers report muscle tension might dissolve.

This indica hybrid can be well-suited for post-work to clear your mind and relax your body. As the high continues, insightful ideas start to flow, and your mind shifts into a heightened state.

Medical smokers report Cherry Pie might assist with depression and PTSD and reduce inflammation. Consuming this cannabis in lower doses may cause sedative sensations and relieve insomnia, helping you drift into slumber.


Strawberry Banana (aka Strawnana)

Strawberry Banana cannabis hybrid strain

The last of the best indica hybrid strains is Strawberry Banana, which contains 70% indica and 30% sativa genetics. This indica-dominant cultivar produces a THC level ranging from 17–23% and is the perfect bud to induce extreme relaxation.

Recreational and medicinal reports that this potent pain-relieving strain can reduce depressive symptoms and anxiety. In lower doses, its high-THC nugs are perfect for increasing appetite and decreasing feelings of fatigue.

Low-tolerance users need to consume Strawnana cautiously as its delightful flavors entice you to take several puffs. As you would expect, this cultivar produces a tropical fruity aroma that blocks up your nostrils.

Once lit, its delectable strawberry smoothie-flavored smoke fills your lungs and lingers in the air. Consumers report that it provides a soothing, calming effect and onset of happiness, which may help drive stress away.

Enjoy the benefits of Strawnana for blissful thoughts before heading off to bed.



Gelato cannabis hybrid strain for 2022

Not only is Gelato feminized a notable strain for its spectacular effects and flavor profile, but it also has an impressive lineage. With parent strains like Thin Mint Cookie and Sunset Sherbert, it’s no wonder this cultivar is so popular. 

Going a little further back, Gelato’s family tree also includes strains like Durban Poison, Cherry Pie, and OG Kush. This diverse combination explains the complex terpene profile that makes up the Gelato strain.

As you’d expect from the name and ancestry, this strain provides a tasty combination of berries, citrus, and sherbert. With each toke, you’ll also enjoy the aroma of cookies and pine, with hints of mint and lavender. 

This mouth-watering treat also packs a potent punch with around 25% THC and should be enjoyed in moderation. Gelato delivers mentally stimulating effects that settle into deeply relaxing laziness. This strain is best suited for veteran connoisseurs to enjoy later in the day. 


Best of both seeds

Are you looking for heavy sedation and relaxation or uplifting and energizing energy? Hybrid strains have many benefits to match any occasion.

Are you looking for a focused creative flow or a stress-busting strain to take the edge off?

Breeders blending cultivars allow us to enjoy the best hybrid strains with various sensations. We get the opportunity to experience the balanced indica, and sativa effects rolled up in one joint.

As you embark on your hybrid cultivation journey, head over to our store for our selection of the best weed hybrid seeds

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